Innovation in Vaccine and Drug Development Processes - 550 Words

Innovation in Vaccine and Drug Development Processes (Essay Sample) Content: Studentà ¢Ã¢â€š ¬s Name:Professor:Course:Date:Innovation in Drug DevelopmentImmune evasion by pathogenic microorganisms has immensely paralyzed the vaccine and drug development processes. Moreover, immune evasion by viruses has infringed the general treatment standards that were initially effective towards the resultant ailments. The core factor resulting in immune evasion by microorganisms is the polymorphic nature of the gene coding for the surface protein that produces an antigen that is detected by the humoral and cell-mediated immunity. In this accord, the influenza virus that resumes various distinct identities has posed a great challenge in drug development, because, it changes two of its surface proteins, hence enabling it to evade the bodyà ¢Ã¢â€š ¬s immune system. In light of this, scientientist have developed a computer program that is capable of targeting the constant region of the viral genome. Hence, this development translated to the designing of a pr otein that eradicates the pathogenicity of the virus. However, the administration of the protein with the capability to eliminate the virulence of the Influenza virus has been tested in mice. In light of this development, this essay seeks to summarize and provide a reflection of David Shultz article, "Computer helps researchers tackle flu strains at once.à ¢Ã¢â€š ¬Ã‚ The development of the computer system that can identify the virusesà ¢Ã¢â€š ¬ constant region is pivotal to the pursuit of antiviral development for other viral strains, regardless of their polymorphic nature. Scientists in PLOS Pathogen have revealed that they have designed a molecule that targets the hemagglutininà ¢Ã¢â€š ¬s vulnerable region exclusively. One of the targeted regions is the epitope protein that constitutes the surface protein. In this accord, the designed molecule is capable of detecting the conserved region of the virus across the diverse strain resulting from mutations. The research that has pro ven to be significant to the drug development process commenced with HB36.5, a small protein molecule that binds to Influenzaà ¢Ã¢â€š ¬s hemagglutinin. Subsequently, using diverse computer algorithms and laboratory assay techniques to test and induce various mutations on the protein HB36.5 to enable it to bind to a wide array of hemagglutinin from different influenza strains (Shultz, 2016).The research translated to a new molecule which had nine mutations, and it is called HB36.6. The molecule was then administered in mice, followed by administration of Influenza Virus. The recombinant mice were then subjected to laboratory analysis. Remarkably, the mice survived the pathogenicity and virulence of the Influenza virus and lost far much less weight as compared to other control experiment done before. However, as the Deborah Fuller, the leader of the study, points out, the success in mice is not directly a reflection of success in humans, but it is a massive breakthrough and a scienti fic realization that could be pivotal to the designing of human antiviruses.In my opinion, the research was an emblem of dedication and progress in the development of antiviruses against pathogenic viruses that are life threatening to human beings....

A Chinese Immigrant Labourer in Vancouver - 550 Words

A Chinese Immigrant Labourer in Vancouver (Essay Sample) Content: A Chinese Immigrant Labourer in VancouverNameInstitutionThe primary objective of this paper is to better comprehend the integration experience of the Chinese immigrant residents in the Vancouver circa and to deduce the views of their residing or moving in the future. Chinese community have comprised the biggest immigrant group in going to Canada since 1925. This research concentrates on the experience of Chinese immigrants from Mainland China and Hong Kong who were highly skilled professionals, and in their country. It shows that these immigrants are being deskilled in the Canada, and this attitude of deskilling is complex by the inconsistent processes of economic restructuring and globalization, with its diverging effects along the axis of race, gender, ethnicity, citizenship and class. Gendered and radicalized institutional procedures in the form of practices, state policies, employers' requirements for the Canadian experience, and labour market situations marginali ze Chinese immigrant and professional accreditation systems (Kotkin, 1993). As an outcome, they are being channelled into part-time, menial, becoming unemployed or insecure positions. In order for the Chinese immigrant to become active and equal participants in the Canadian society, provisions of inclusive policies and programs is important. This longitudinal research examined the effects of discrimination on socio-emotional modifications and the academic performances for Chinese immigrants. Using cross-lagged and an autoregressive technique, results demonstrate that the discrimination in immigrants predicted alienation, depressive symptoms, grades in middle adolescence and school engagement. Further, investigations of whether contemporaneous or earlier experiences of discrimination prejudiced developmental results in immigrants indicated differential consequences, with contemporaneous proficiencies of discrimination affecting the socio-emotional adjustments, whilst earlier discrimi nation effect was more important for academic performances. This immigrant group had an extensive-term time prospect if we imitate on their inspirations to migrate to the Vancouver. They came into Canada to be Canadian citizens, relish the natural ecology and train their children. Hastily, these motivations seem to replicate the traditional objectives of the Canadas past settlers whose purpose was to remain permanently seemingly in the Canada. Nonetheless, there exists one more understanding that is more reliable with the activities of Statistics Canada (2003) that suggests that these inspirations are those of the sojourner immigrant that when experienced with short-term commercial exigencies, might later be desirous to leave Vancouver (Statistics Canada, 2003).This study argues that prosperous integration into the Vancouver of the Chinese immigrants varies with the ability to achieve their initial objectives. An analysis of their experiences indicates marital status, procuring at l east a single degree in the Canada state and having high income entirely increased the likelihood of...